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1748 : Bruton's Tyrosine Kinase Inhibitors Impair Fcγriia-Mediated Responses of Healthy Donor Platelets and Chronic Lymphocytic Leukaemia Derived Platelets to Bacteria

Researchers

Presenter

  • Leigh Naylor-Adamson

Principal Investigators

  • Zoe Booth

  • Simon Hart

  • Russell Patmore

  • Sujoy Khan

  • David Allsup

  • Monica Arman

Medical Centers

  • Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, Owston Ferry, ENG, United Kingdom

  • Centre for Atherothrombosis and Metabolic Disease, University of Hull, Hull, ENG, United Kingdom

  • Respiratory Research Group, Hull York Medical School, Cottingham, United Kingdom,

  • Department of Rheumatology, Hull and East Yorkshire NHS Trust, Hull East Yorkshire, United Kingdom

  • Department of Immunology & Allergy, Hull and East Yorkshire Hospitals NHS Trust, Hull, ENG, United Kingdom

  • Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, Owston Ferry, ENG, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Chronic Lymphocytic Leukemia

Biomarkers

  • Immunoglobulin G

Drug/Treatment

  • ACP-196

  • Ibrutinib

  • Evithrom

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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