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160 : ALLCAR19: Updated Data Using AUTO1, a Novel Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies

Researchers

Presenter

  • Claire Roddie

Principal Investigators

  • Maria A V Marzolini

  • Leigh Wood

  • Juliana Dias

  • Amaia Cadinanos Garai

  • Leticia Bosshard

  • Mahnaz Abbasian

  • Mark W. Lowdell

  • Graham Wheeler

  • Joanna Olejnik

  • Bilyana Popova

  • Laura Clifton-Hadley

  • Yashma Pathak

  • Victoria Spanswick

  • Helen Lowe

  • John A. Hartley

  • Farhatullah Syed

  • Waseem Qasim

  • Farzin Farzaneh

  • David C. Linch

  • Martin Pule

  • Karl S Peggs

Medical Centers

  • Department of Haematology, Clinical Lead, CAR-T, University College London Hospitals Senior Lecturer in Haematology, University College London NHS Foundation Trust, London, United Kingdom

  • Department of Urology, King's College Hospital NHS Foundation Trust, London, United Kingdom

  • Bart's Cancer Institute, London, United Kingdom

  • Kings College London, London, United Kingdom

  • UCL Cancer Institute, University College London,, London, United Kingdom

  • Cellular Therapeutics, University College London, London, United Kingdom

  • Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom

  • CRUK and UCL Cancer Trials Centre, London, United Kingdom

  • CRUK and UCL Cancer Trials Centre, London, United Kingdom

  • Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom

  • UCL Cancer Institute, University College London,, London, United Kingdom

  • Kings College London, London, United Kingdom

  • Institute of Child Health, UCL, London, ENG, United Kingdom

  • Kings College London, London, United Kingdom

  • University College London Hospitals/UCL Cancer Institute, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Cytokine release syndrome

  • B cell lymphomas

Biomarkers

  • Cluster of Differentiation 19

  • Coxsackie Virus And Adenovirus Receptor

  • Cytokine

  • Twist-related protein 1

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • fludarabine tablet

Outcome

  • N/A


Study Design

  • N/A

Phase

  • I

Study Id's

  • NCT02935257

Sponsors

  • N/A

Result

  • N/A