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1518 : Improving Donor Selection for Haploidentical Stem Cell Transplantation with Post-Transplant Cyclophosphamide through Selective HLA-Mis/Matching

Researchers

Presenter

  • Ephraim J. Fuchs

Principal Investigators

  • Shannon R McCurdy

  • Scott R. Solomon

  • Tao Wang

  • Michelle Kuxhausen

  • Yvette L Kasamon

  • Monzr M. Al Malki

  • Shahinaz Gadalla

  • Sophie Paczesny

  • Steven GE Marsh

  • Bronwen E. Shaw

  • Stephen R. Spellman

  • Stephanie J. Lee

  • Effie Petersdorf

Medical Centers

  • The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD

  • The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD

  • The Blood and Marrow Transplant Program at Northside Hospital, Atlanta, GA

  • The Medical College of Wisconsin, Milwaukee, WI

  • Center for International Blood and Marrow Transplant Research, Minneapolis, MN.

  • Department of Hematology and Hematopietic Cell Transplantation, City of Hope, Duarte, CA

  • Division of Cancer Epidemiology & Genetics, NIH-NCI Clinical Genetics Branch, Rockville, MD

  • Indiana University School of Medicine, Indianapolis, IN

  • Anthony Nolan Research Institute & University College London Cancer Institute, Royal Free Campus, London, United Kingdom

  • Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI

  • Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI

  • Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA

  • Fred Hutchinson Cancer Resaerch Center, Seattle, WA

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Blood/haematological Diseases

Disease

  • Alpha-thalassemia myelodysplasia syndrome

  • Acute Leukemia

Biomarkers

  • Major histocompatibility complex, class II, DR beta 1

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

Outcome

  • N/A

Study Design

  • Multinational

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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