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1468 : Increased Incidence of New-Onset Diabetes Mellitus Type II Following Haploidentical Bone Marrow Transplant with Post-Transplant Cyclophosphamide for Sickle Cell Disease

Researchers

Presenter

  • Dilan A Patel

Principal Investigators

  • Michael Matheney

  • Leena Karnik

  • Heidi Chen

  • Katie S. Gatwood

  • Kathryn A. Culos

  • Karina L Wilkerson

  • Michael T. Byrne

  • Salyka M. Sengsayadeth

  • Stacey Ann Goodman

  • Bhagirathbhai Dholaria

  • Bipin N. Savani

  • Wichai Chinratanalab

  • Reena Jayani

  • Jim Connelly

  • Carrie Lynn Kitko

  • Brian G. Engelhardt

  • Adetola A. Kassim

Medical Centers

  • Department of Hematology and Bone Marrow Transplant, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN

  • Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom

  • The University of Tennessee Health Science Center, Memphis, TN

  • Paediatrics, St Mary's Hospital, London, United Kingdom

  • Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN

  • Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN

  • Hematology/Oncology Department Sickle Cell Disease Center of Excellence, Vanderbilt University Medical Center, Nashville, TN

  • Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN

  • Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN

  • Vanderbilt University Medical Center, Nashville, TN

  • Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN

  • Department of Medicine, Division of Hematology-Oncology, Vanderbilt University, Brentwood, TN

  • 2Vanderbilt University Medical Center,

  • Department of Pediatrics/Div of Hematology/Oncology, Vanderbilt University, Nashville, TN

  • Vanderbilt University Medical Center, Nashville, TN

  • Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

  • Autoimmune (AI)

Disease

  • Type 2 diabetes mellitus

  • Sickle cell anemia

  • Diabetes

  • Post-transplant diabetes mellitus

Biomarkers

  • Stearoyl-CoA desaturase

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Oraprine

  • Hydroxyurea

  • Hydroxycarbamide

Outcome

  • N/A

Study Design

  • Multicenteric

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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