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1358 : Preclinical and Translational Support for Clinical Development of Iberdomide in Combination with Proteasome Inhibitors: Mechanism of Synergy in Clinical Trial CC-220-MM-001

Researchers

Presenter

  • Michael Amatangelo

Principal Investigators

  • Jian Kang

  • Archana Mukhopadhyay

  • Mara Dolores Jimnez Nuez

  • Lilly Wong

  • William Pierceall

  • Sagar Lonial

  • Niels W.C.J. Van De Donk

  • Rakesh Popat

  • Sundar Jagannath

  • Jeffrey Zonder

  • Monique C. Minnema

  • Albert Oriol

  • Jeremy Larsen

  • Ashraf Z. Badros

  • Paula Rodriguez-Otero

  • Pieter Sonneveld

  • Tuong Vi Nguyen

  • Kevin Hong

  • April Sorrell

  • Anjan Thakurta

Medical Centers

  • Bristol-Myers Sqiubb, Princeton, NJ

  • Celgene Research SLU, A Bristol-Myers Squibb Company, Seville, CA, Spain

  • Winship Cancer Institute of Emory University, Atlanta, GA

  • Department of Hematology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, Netherlands

  • NIHR Clinical Research Facility, University College London Hospitals, London, United Kingdom

  • Mount Sinai Hospital, New York, NY

  • Karmanos Cancer Institute, Detroit, MI

  • Department of Medical Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands

  • Institut d’Investigació Contra la Leucèmia Josep Carreras and Institut Català d’Oncologia, Hospital Germans Trias i Pujol, Badalona, Spain

  • Mayo Clinic, Scottsdale, AZ

  • The University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland Medical Center, Baltimore, MD

  • Clinica Universidad de Navarra-CIMA, IDISNA, CIBERONC, Pamplona, Spain

  • Erasmus University Medical Center, Rotterdam, Netherlands

Locations

  • United States

  • Spain

  • Netherlands

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Peripheral blood mononuclear cell

Drug/Treatment

  • Pomalidomide

  • CC-4047

  • Lenalidomide

  • CC-220

Outcome

  • N/A

Study Design

  • N/A

Phase

  • I/II

Study Id's

  • NCT02773030

Sponsors

  • N/A

Result

  • N/A

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