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: A subset of COPD patients defined by lung epithelial IL-6 trans-signalling is associated with neutrophilic inflammation and colonization by Haemophilus influenzae

Researchers

Presenter

  • Zala Jevnikar Rojnik

Principal Investigators

  • Sarah Diver

  • Chris Brightling

  • Henric Olsson

Medical Centers

  • Translational Science and Experimental Medicine, Research and Early Development, Respiratory, Inflammation and Autoimmune (RIA, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden, Gothenburg, Sweden

  • Institute for Lung Health, NIHR Leicester Biomedical Research Centre, Department of Respiratory Science, University of Leicester and University Hospitals of Leicester NHS Trust, Leicester, United Kingdom, Leicester, United Kingdom

Locations

  • Sweden

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

Disease

  • Asthma

  • Chronic obstructive pulmonary disease

Biomarkers

  • Interleukin 1 beta

  • Interleukin 6

  • Interleukin-8

  • Matrix metalloproteinase

Drug/Treatment

  • Immunol

Outcome

  • N/A


Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A