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P025 : The Paradigms Study: A Randomized Double-Blind Trial of Fingolimod Versus Interferon β-1a in Patients with Multiple Sclerosis Aged 10 to < 18 Years

Researchers

Presenter

  • Tanuja Chitnis

Principal Investigators

  • Douglas L. Arnold

  • Brenda Banwell

  • Wolfgang Bruck

  • Angelo Ghezzi

  • Gavin Giovannoni

  • Benjamin Greenberg

  • Lauren B Krupp

  • Kevin Rostasy

  • Marc Tardieu

  • Emmanuelle Waubant

  • Jerry S Wolinsky

  • Amit Bar-Or

  • Tracy Stites

  • Martin Merschhemke

  • Jutta Grtner

Medical Centers

  • Massachusetts General Hospital, Boston, MA

  • McGill University, Montreal, QC, Canada; NeuroRx Research, Montreal, QC, Canada

  • Childrens Hospital of Philadelphia, Philadelphia, PA

  • University Medical Center Goettingen, Gottingen, Germany

  • 4Ospedale di Gallarate Gallarate Italy

  • Barts and the London School of Medicine, London, United Kingdom

  • The University of Texas Southwestern, Dallas, TX

  • New York University Medical Center, New York City, NY

  • Children’s Hospital Datteln, University Witten/Herdecke, Datteln, Germany

  • GHU Paris-Sud - Hôpital de Bicêtre, Bicêtre, France

  • University of California, San Francisco, San Francisco, CA

  • McGovern Medical School, Houston, TX

  • Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

  • Novartis Pharmaceutical Corporation, East Hanover, NJ

  • Novartis AG, Basel, Switzerland

  • University Medical Center Goettingen, Gottingen, Germany

Locations

  • United States

  • Canada

  • Germany

  • Italy

  • United Kingdom

  • France

  • Switzerland

Companies

  • Novartis AG

Study Components

Therapeutic Area

  • Dermatology

  • Genetic Disorder

Disease

  • Multiple Sclerosis

  • Ectodermal dysplasia-syndactyly syndrome

Biomarkers

  • Interferon

Drug/Treatment

  • Fingolimod

  • Interferon

  • IFN-lambda

Outcome

  • N/A

Study Design

  • Randomized

  • Double Blind/Blinded

  • Open Label

  • Controlled

  • Parallel Group

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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