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: Macitentan for inoperable chronic thromboembolic pulmonary hypertension (CTEPH): results from the randomised controlled MERIT study

Researchers

Presenter

  • Grald Simonneau

Principal Investigators

  • Zhi C. Jing

  • Andrea M. D'Armini

  • Peter Fedullo

  • Luke Howard

  • Xavier Jas

  • David P. Jenkins

  • Nick H. Kim

  • Michael Madani

  • Nicholas Martin

  • Eckhard Mayer

  • Kelly Papadakis

  • Dominik Richard

  • Hossein A. Ghofrani

Medical Centers

  • Assistance Publique–Hôpitaux de Paris, Service de Pneumologie, Hôpital Bicêtre, Université Paris-Sud, Laboratoire d’Excellence en Recherche sur le Médicament et Innovation Thérapeutique, and INSERM Unité 999, Le Kremlin–Bicêtre, France,

  • State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Centre for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  • Department of Cardio-Thoracic and Vascular Surgery, Heart and Lung Transplantation and Pulmonary Hypertension Unit, Foundation “I.R.C.C.S. Policlinico San Matteo”, University of Pavia School of Medicine, Pavia, Italy

  • Division of Pulmonary and Critical Care Medicine, University of California, San Diego, La Jolla, United States

  • National Pulmonary Hypertension Service, Imperial College Healthcare NHS Trust, Hammersmith Hospital; National Heart & Lung Institute, Imperial College London, London, United Kingdom

  • Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre; Faculté de Médecine Paris-Sud, Université Paris-Sud, Université Paris-Saclay; Inserm UMR-S 999, Hôpital Marie Lannelongue, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France

  • Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom

  • Division of Cardiovascular and Thoracic Surgery, University of California San Diego Medical Center, San Diego, United States of America

  • Actelion Pharmaceuticals Ltd, Allschwil, Switzerland

  • Department of Cardiac Surgery, Kerckhoff-Klinik, Bad Nauheim, Germany

  • University of Giessen and Marburg Lung Center, Giessen, Germany, member of the German Center for Lung Research (DZL), Department of Medicine, Imperial College London, London, United Kingdom.

Locations

  • France

  • China

  • Italy

  • United States

  • United Kingdom

  • Switzerland

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Pulmonary/Respiratory Diseases

Disease

  • Chronic thromboembolic pulmonary hypertension

Biomarkers

  • N/A

Drug/Treatment

  • macitentan

Outcome

  • N/A

Study Design

  • Randomized

  • Placebo Control

  • Double Blind/Blinded

  • Controlled

Phase

  • NA

Study Id's

  • NCT02021292

Sponsors

  • N/A

Result

  • N/A

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