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: Phosphoinositide-3-kinase gamma/delta isoform signalling defines a mixed T cell severe asthmatic endotype

Researchers

Presenter

  • Matt Thomas

Principal Investigators

  • Karin Bjorhall

  • Elisabeth Israelsson

  • Eva LammBergstrom

  • Jay Horvat

  • Richard Kim

  • Rose Maciewicz

  • Daniel Muthas

  • Maria Nordberg

  • Sandra RodrigoBlomqvist

  • Tiiu Saarne

  • Carla Winkler

  • Kostas Karabelas

  • Ian Adcock

  • Fan Chung

  • Philip Hansbro

  • Anna Malmgren

  • Matthew Perry

Medical Centers

  • AstraZeneca, Gothenburg, Sweden

  • University of Newcastle, Newcastle, Australia

  • Imperial College, London, United Kingdom

Locations

  • Sweden

  • Australia

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Asthma

Biomarkers

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Interferon-gamma

  • Interleukin 17A

  • Interleukin 5

  • Interleukin-8

  • T cell activity

Drug/Treatment

  • GM-CSF

  • Interferon Gamma

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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