// App-Quantinova.ai

TPS189 : PLANETTE: A modular phase IIa multicenter open-label study evaluating the ATR inhibitor ceralasertib (AZD6738) in ATM mutant advanced solid tumors.

Researchers

Presenter

  • Wassim Abida

Principal Investigators

  • Elkhan Sanay

  • Natalia Lukashchuk

  • Andrew Pierce

  • Wessel de Graaf

  • Alan Lau

  • Vidalba Rocher Ros

  • Nisha Kurian

  • Graeme Parr

  • Bienvenu LoembE

  • Emma Dean

  • Rahul Raj Aggarwal

Medical Centers

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

  • University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Solid malignancies

  • Unspecified Cancer

  • Metastatic castration-resistant prostate cancer

  • Prostate cancer

  • Non Small Cell Lung cancer

Biomarkers

  • Ataxia Telangiectasia And Rad3-Related Protein

  • Circulating tumor cells

  • Prostate specific antigen

  • Ataxia-telangiectasia mutated

Drug/Treatment

  • AZD6738

Outcome

  • N/A

Study Design

  • Pharmacodynamics

  • Open Label

  • Multicenteric

  • Cohort

Phase

  • II

Study Id's

  • NCT02576444

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved