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1877 : Serum HBsAg levels predict the severity of liver fibrosis among HBeAg‐positive patients across all major HBV genotypes and among patients with low ALT levels: results from the SONIC‐B cohort

Researchers

Presenter

  • Milan J. Sonneveld

Principal Investigators

  • Willem Pieter Brouwer

  • Henry Lik- Yuen Chan

  • Teerha Piratvisuth

  • Jidong Jia

  • Stefan Zeuzem

  • Yun-Fan Liaw

  • Bettina E. Hansen

  • Cynthia Wat

  • Qing Xie

  • Patrick Marcellin

  • Robert J. de Knegt

  • Harry L. Janssen

Medical Centers

  • Erasmus University Medical Center, Rotterdam, Netherlands

  • The Chinese University of Hong Kong, Hong Kong SAR, China

  • Songkla university, Hat Yai, Thailand

  • Beijing Friendship Hospital, Beijing, China

  • Goethe University Medical Center, Frankfurt, Germany

  • Chang Gung Memorial Hospital, Taipei, Taiwan

  • University of Toronto, Toronto, ON, Canada

  • Bichat Hospital, Paris, France

  • Roche Products Ltd., Welwyn Garden City, United Kingdom

  • Shanghai Renji Hospital, Shanghai, China

Locations

  • Netherlands

  • China

  • Thailand

  • Germany

  • Taiwan

  • Canada

  • France

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

Disease

  • Hepatitis B

  • Hepatic fibrosis

Biomarkers

  • Alanine transaminase

  • Aspartate aminotransferase

  • Human albumin

  • Hepatitis B surface antigen

  • Hepatitis B e antigen

  • Serum hepatitis B virus DNA

Drug/Treatment

  • Alkaline phosphatase

Outcome

  • N/A


Study Design

  • Randomized

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A