// App-Quantinova.ai

45 : Multiple HLA B*57 alleles, sharing the amino acid residue Valine97, are associated with drug‐induced liver injury due to flucloxacillin in a European population.

Researchers

Presenter

  • Paola Nicoletti

Principal Investigators

  • Guruprasad P. Aithal. Sally Coulthard

  • Raul Andrade

  • Bjornsson S. Einar

  • John Dillon

  • Anke H. Maitland-van der Zee

  • Jennifer H. Martin

  • Mariam Molokhia

  • Munir Pirmohamed

  • Mia Wadelius

  • Aris Floratos

  • Yufeng Shen

  • Matthew R. Nelson

  • Ann K. Daly

Medical Centers

  • Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom

  • UGC Digestivo, Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, Spain

  • Dept. of Respiratory Medicine and Sleep, Landspitali University Hospital, Reykjavik, Iceland

  • Medical Research Institute, University of Dundee, Dundee, United Kingdom

  • Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, Netherlands

  • and School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia

  • Primary Care and Public Health Sciences, Kings College London, London, United Kingdom

  • Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

  • Rheumatology, Department of Medical Sciences and Science for Life Laboratory, Uppsala University, Uppsala, Sweden

  • Department of Pathology, Columbia University, New York, NY

  • Target Sciences, GSK, Pennsylvania, PA

  • Liver and GI Theme, NIHR Nottingham Biomedical Research Centre, Nottingham, United Kingdom

  • Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, United Kingdom

Locations

  • United Kingdom

  • Spain

  • Iceland

  • Netherlands

  • Australia

  • Sweden

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Gastroenterology (GU)

Disease

  • Drug-induced liver injury

Biomarkers

  • N/A

Drug/Treatment

  • Flopen

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved