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TPS480 : A phase II open-label study in adult and adolescent patients (pts) with advanced solid tumors harboring fibroblast growth factor receptor (FGFR) gene alterations.

Researchers

Presenter

  • Shubham Pant

Principal Investigators

  • Josep Tabernero

  • Christophe Massard

  • Gopa Iyer

  • Olaf Witt

  • Toshihiko Doi

  • Shukui Qin

  • Christine Lu-Emerson

  • Darren R. Hargrave

  • Javier Garca-Corbacho

  • Shonda Marie Little

  • Qi Xia

  • Ademi E. Santiago-Walker

  • Christopher Moy

  • Constance Hammond

  • Hussein Sweiti

  • Martin H. Schuler

Medical Centers

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • Vall dHebron University Hospital Institute of Oncology, Barcelona, Spain

  • Gustave Roussy Cancer Campus and University Paris-Sud, Villejuif, France

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

  • KiTZ Clinical Trial Unit, Hopp Childrens Cancer Center at the NCT Heidelberg (KiTZ), German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany

  • National Cancer Center Hospital, Tokyo, Japan

  • The Chinese People's Liberation Army 81 Hospital, Nanjing, China

  • Maine Medical Partners Neurology & Tufts University School of Medicine, Scarborough, ME

  • Great Ormond Street Institute of Child Health, UCL, London, United Kingdom

  • Hospital Clinic de Barcelona, Translational Genomics and Targeted Therapeutics in Solid Tumours Lab (IDIBAPS), Barcelona, Spain

  • GlaxoSmithKline, Royersford, PA

  • Janssen Research & Development, LLC, USA, Philadelphia, PA

  • Janssen Research and Development, LLC, Spring House, PA

  • Janssen Research and Development, LLC, Spring House, PA

  • Janssen, Dusseldorf, Germany

  • Department of Surgery, Westgerman Cancer Center, University Hospital Essen, Essen, Germany

Locations

  • United States

  • Spain

  • France

  • Germany

  • Japan

  • China

  • United Kingdom

Companies

  • JB Medical Ltd.

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Fibroblast growth factor receptor

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Pharmacokinetics

  • Open Label

  • Cohort

Phase

  • II

Study Id's

  • NCT04083976

Sponsors

  • N/A

Result

  • N/A

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