// App-Quantinova.ai

228 : A monoclonal antibody against BDCA-2 inhibits TLR-induced activation of human pDC in vitro and in vivo: a novel therapeutic target for systemic sclerosis

Researchers

Presenter

  • Clarissa Corinaldesi

Principal Investigators

  • Yasser M El-Sherbiny

  • Gemma Migneco

  • Rebecca L Ross

  • Antonio Carriero

  • Clive McKimmie

  • Francesco Del Galdo

Medical Centers

  • Institute of Rheumatic and Musculoskeletal Medicine, Biomedical Research Centre LTHT, University of Leeds, Leeds, UNITED KINGDOM

  • NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals, NHS Trust, Chapel Allerton Hospital, Leeds, UNITED KINGDOM

  • Institute of Cancer and Pathology, University of Leeds, Leeds, UNITED KINGDOM

  • Virus Host Interactions Team, Section of Infection and Immunity, University of Leeds, Leeds, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Scleroderma

Biomarkers

  • Peripheral blood mononuclear cell

  • Immunoglobulin G

Drug/Treatment

  • Imiquimod

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved