// App-Quantinova.ai

23 : Generation and validation of an in vitro model of Langhans-type multinucleated giant cells to investigate giant cell arteritis

Researchers

Presenter

  • Daniel Maunder

Principal Investigators

  • Emily Stephenson

  • Rachel Botting

  • James Fletcher

  • Alice R Lorenzi

  • Ben Thompson

  • Jonathan Heaney

  • Alexandra-Chloe Villani

  • John D Isaacs

  • Muzlifah Haniffa

  • Gary Reynolds

Medical Centers

  • Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UNITED KINGDOM

  • Rheumatology Department, Freeman Hospital, Newcastle-Upon-Tyne, UNITED KINGDOM

  • Center for Immunolgy and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Autoimmune (AI)

Disease

  • Giant cell arteritis

Biomarkers

  • Cluster of Differentiation 14

  • Proto-oncogene tyrosine-protein kinase ROS

  • Granulocyte-macrophage-colony stimulating factor

  • Interferon-gamma

  • Interleukin 6

Drug/Treatment

  • GM-CSF

  • Interferon Gamma

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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