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O07 : Anti-CD3 and p38 inhibition as a potential novel combination therapy acting to boost CD8 regulatory T cells whilst minimising inflammatory cytokine release in rheumatoid arthritis

Researchers

Presenter

  • Anna Zarafov

Principal Investigators

  • Michael R Ehrenstein

Medical Centers

  • Academic Neonatology, University College London, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Rheumatoid arthritis

Biomarkers

  • Peripheral blood mononuclear cell

  • Cluster of Differentiation 4

  • Cluster of differentiation 8A

  • Interleukin 1

  • Interleukin 6

  • Regulatory T cells

Drug/Treatment

  • Adalimumab

  • Etanercept

  • CHS-0214

  • losmapimod

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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