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14219 : Oxidation of PKA-RIα Protects Against Ischemia-reperfusion Injury by Inhibiting Lysosomal-triggered Calcium Release

Researchers

Presenter

  • Jillian N Simon

Principal Investigators

  • BESARTE VRELLAKU

  • Stefania Monterisi

  • Sandy Chu

  • Nadiia Rawlings

  • Oliver Lomas

  • Gerard A Marchal

  • Dominic Waithe

  • Parag R Gajendragadkar

  • Raja Jayaram

  • Rana Sayeed

  • Keith M Channon

  • Pawel Swietach

  • Manuela Zaccolo

  • Phil Eaton

  • Barbara Casadei

Medical Centers

  • Radcliffe Dept of Medicine, Div of Cardiovascular Medicine, Univ of Oxford, Oxford, United Kingdom

  • Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

  • Wolfson Imaging Centre, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK

  • Oxford Cancer Centre, Oxford, United Kingdom

  • William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Ischemia-reperfusion injury

  • Coronary Artery Disease

Biomarkers

  • N/A

Drug/Treatment

  • tetracaine

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A