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EXTH-44 : DEVELOPMENT OF RETROVIRAL REPLICATING VECTORS ENCODING SEQUENCE-OPTIMIZED NITROREDUCTASE FOR PRODRUG ACTIVATOR GENE THERAPY IN HUMAN GLIOMA MODELS

Researchers

Presenter

  • Sara Collins

Principal Investigators

  • Akihito Inagaki

  • Chien-Kuo Tai

  • Christopher R Logg

  • Peter Searle

  • Mark Tangney

  • Noriyuki Kasahara

Medical Centers

  • University of California, San Francisco, San Francisco, CA

  • National Chung Cheng University, Chia-Yi, Taiwan (Republic of China)

  • UCLA, Los Angeles, CA

  • School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom

  • Cork Cancer Research Centre, University College Cork (UCC), Cork, Ireland

Locations

  • United States

  • Republic of South Korea

  • United Kingdom

  • Ireland

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • High-Grade Gliomas

Biomarkers

  • N/A

Drug/Treatment

  • vocimagene amiretrorepvec + Toca FC

  • EGFRvIII

  • CB1954

Outcome

  • N/A

Study Design

  • Multinational

Phase

  • III

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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