// App-Quantinova.ai

LBA-5 : ANCHOR CRC: a single-arm, phase 2 study of encorafenib, binimetinib plus cetuximab in previously untreated BRAF V600E-mutant metastatic colorectal cancer

Researchers

Presenter

  • A. Grothey

Principal Investigators

  • J. Taieb

  • R. Yaeger

  • T. Yoshino

  • E. Maiello

  • E. Elez Fernandez

  • A. Ruiz Casado

  • P. Ross

  • T. Andr

  • T. Kato

  • J. Ruffinelli

  • J. Graham

  • M. Van den Eynde

  • R. Vera

  • B. Jean

  • E. Carriere Roussel

  • C. Cahuzac

  • Z. Issiakhem

  • J. Vedovato

  • E. Van Cutsem

Medical Centers

  • West Cancer Center, University of Tennessee, Germantown, TN

  • Vall d Hebron University Hospital (HUVH) and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain

  • Paris Descartes University, Georges Pompidou European Hospital, Paris, France

  • Memorial Sloan-Kettering Cancer Center, New York, NY, United States

  • Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan, Kashiwa, Japan

  • Hematology and BMT Unit, Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy

  • Vall dHebron Institute of Oncology, Universitat Autonoma de Barcelona, Barcelona, Spain

  • Puerta de Hierro University Hospital, Majadahonda, Spain

  • Guy's And St Thomas NHS Foundation Trust, London, United Kingdom

  • Sorbonne University, Medical oncology department, AP-HP, Saint-Antoine hospital, Paris, France

  • Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan

  • Catalan Institute of Oncology, Hospital Duran i Reynals, L?Hospitalet, Spain

  • Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

  • Universite Catholique de Louvain, Bruxelles, Belgium

  • Complejo Hospitalario de Navarra, Pamplona, Spain

  • Pierre Fabre Laboratories, Boulogne Billancourt, France

  • University Hospitals Leuven and KU Leuven, Leuven, Belgium

Locations

  • United States

  • Spain

  • France

  • Japan

  • Italy

  • United Kingdom

  • Belgium

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Gastroenterology (GU)

Disease

  • Colorectal Cancer

Biomarkers

  • B-Raf proto-oncogene, serine/threonine kinase

Drug/Treatment

  • Binimetinib

  • Encorafenib

  • Erbitux

Outcome

  • N/A

Study Design

  • Open Label

  • Single Arm

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved