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CT286 : Canakinumab (Cana) in patients (pts) with non-small cell lung cancer (NSCLC)

Researchers

Presenter

  • Luis Paz-Ares

Principal Investigators

  • Tony Mok

  • Andrea Ardizzoni

  • Fabrice Barlesi

  • Byoung Chul Cho

  • Gilberto de Castro

  • Pedro De Marchi

  • Enriqueta Felip

  • Yasushi Goto

  • Alastair Greystoke

  • Shun Lu

  • Darren Wan-Teck Lim

  • Martin Reck

  • Benjamin J. Solomon

  • David R. Spigel

  • Daniel SW Tan

  • Michael Thomas

  • James Chih-Hsin Yang

  • Jay M. Lee

  • Pilar Garrido

  • Edward Kim

  • Bruce E. Johnson

Medical Centers

  • University Hospital 12 de October, Madrid, Spain

  • David Geffen School of Medicine at UCLA/TRIO-US Network, Los Angeles, CA

  • The Chinese University of Hong Kong, Hong Kong, Hong Kong

  • St. Orsola-Malpighi University Polyclinic, Bologna, Italy

  • Aix Marseille University, Marseille, France

  • Yonsei University College of Medicine, Seoul, Korea

  • Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, Brazil

  • H Cancer de Barretos, Barretos, Brazil

  • Vall d'Hebron Institute of Oncology, Barcelona, Spain

  • National Cancer Center Hospital Department of Thoracic Oncology, Tokyo, Japan

  • Newcastle upon Tyne Hospitals Trust, Newcastle upon Tyne, United Kingdom

  • Shanghai Chest Hospital, Jiao Tong University, Shanghai, China

  • National Cancer Centre Singapore, Singapore, Singapore

  • LungenClinic, Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany

  • Peter MacCallum Cancer Centre, East Melbourne, Australia

  • Sarah Cannon Research Institute, Nashville, TN

  • Internistische Onkologie der Thoraxtumoren, Thoraxklinik im Universitätsklinikum Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Heidelberg, Germany

  • Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan

  • University of California, Los Angeles, Los Angeles, CA

  • Hospital Universitario Ramon y Cajal, Madrid, Spain

  • Levine Cancer Institute, Charlotte, SC

  • Dana-Farber Cancer Institute, Boston, MA

Locations

  • Spain

  • United States

  • Hong Kong

  • Italy

  • France

  • Republic of South Korea

  • Brazil

  • Japan

  • United Kingdom

  • China

  • Singapore

  • Germany

  • Australia

  • Taiwan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Non Small Cell Lung cancer

Biomarkers

  • Anaplastic lymphoma Kinase

  • Programmed death-ligand 1

  • Epidermal growth factor receptor

Drug/Treatment

  • Pembrolizumab

  • canakinumab (SC)

  • Pemetrexed

  • Docetaxel

  • Cisplatin

Outcome

  • N/A


Study Design

  • Randomized

  • Placebo Control

  • Double Blind/Blinded

  • Open Label

  • Multicenteric

  • Controlled

Phase

  • III

Study Id's

  • NCT03968419

  • NCT03447769

  • NCT03631199

  • NCT03626545

Sponsors

  • N/A

Result

  • N/A