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4547 : Clustering CD137 via cell-expressed PD-L1 crosslinking avoided Fc-mediated agonism and resulted in safe and potent conditional lymphocyte activation

Researchers

Presenter

  • Matthew A. Lakins

Principal Investigators

  • Alexander Koers

  • Raffaella Giambalvo

  • Robert Hughes

  • Sylwia Marshall

  • Mateusz Wydro

  • Cristian Gradinaru

  • Sarah Batey

  • Daniel Gliddon

  • Michelle Morrow

  • Neil Brewis

Medical Centers

  • F-star Biotechnology Ltd, Cambridge, United Kingdom.

Locations

  • United Kingdom

Companies

  • F-star Biotechnology

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Programmed death-ligand 1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Pharmacokinetics

  • Pharmacodynamics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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