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245 : Glutamine fuels the TCA cycle in VHL and FH mutant renal cell carcinoma

Researchers

Presenter

  • Akash K. Kaushik

Principal Investigators

  • Cissy Yong

  • Mukundan Ragavan

  • Christina Stevens

  • Layton Woolford

  • Aparna Rao

  • Brandon Faubert

  • Panayotis Pachnis

  • Lauren Zacharias

  • Hieu Vu

  • Matthew Merritt

  • James Brugarolas

  • Ralph J. DeBerardinis

Medical Centers

  • UTSouthwestern Medical Center, Dallas, TX

  • University of Cambridge, Cambridge, United Kingdom

  • University of Florida, FL

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Renal cell carcinoma

  • Clear cell renal carcinoma

  • Solid malignancies

Biomarkers

  • Glutamine

  • Isocitrate dehydrogenase 1

  • Isocitrate dehydrogenase 2

  • X-Ray Repair Cross Complementing 1

Drug/Treatment

  • Glutamine

  • CB-839

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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