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3415 : Mutant BRAF small molecule inhibition enhances oncolytic herpes virus immunotherapy through increased immune cell recruitment and activation in melanoma

Researchers

Presenter

  • Galabina Bozhanova

Principal Investigators

  • Victoria Jennings

  • Malin Pedersen

  • Joan Kyula

  • Emmanuel Patin

  • Jehanne Hassan

  • Masahiro Ono

  • Kevin Harrington

  • Alan Melcher

Medical Centers

  • Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Melanoma

  • Solid malignancies

Biomarkers

  • Mitogen-activated protein kinase

  • B-Raf proto-oncogene, serine/threonine kinase

  • Programmed death-ligand 1

  • Cluster of differentiation 8A

  • Regulatory T cells

  • T-cell receptor

Drug/Treatment

  • HSV1716

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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