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5720 : MicroRNA deregulation of the serine synthesis pathway controls intrinsic and non-cell autonomous mechanism of resistance to Regorafenib in metastatic colorectal cancer (mCRC)

Researchers

Presenter

  • Somaieh Hedayat

Principal Investigators

  • Andrea Lampis

  • George Vlachogiannis

  • khurum Khan

  • Silvia Marchetti

  • Matteo Fassan

  • Michele Ghidini

  • Ruwaida Begum

  • Marta Schirripa

  • Rodolfo Passalacqua

  • David Cunningham

  • Fotios Loupakis

  • Nicola Valeri

Medical Centers

  • Institute for Cancer Research, London, United Kingdom

  • The Royal Marsden Hospital NHS Foundation Trust, London & Surrey, United Kingdom

  • Surgical Pathology and Cytopathology Unit, University of Padua, Italy

  • Azienda Ospedaliera di Cosenza, Cosenza, Italy

  • The Royal Marsden Hospital, London, United Kingdom

  • Istituto Oncologico Veneto – IRCCS, Padua, Sutton, Italy

  • Azienda Ospedaliera di Cosenza, Cosenza, Italy

Locations

  • United Kingdom

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Gastroenterology (GU)

Disease

  • Colorectal Cancer

Biomarkers

  • N/A

Drug/Treatment

  • Regorafenib

Outcome

  • N/A

Study Design

  • Cohort

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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