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3547 : Frequent genomic alterations to evade the immune system in colorectal cancer with POLE gene mutation

Researchers

Presenter

  • Yoshikage Inoue

Principal Investigators

  • Nobuyuki Kakiuchi

  • Kenichi Yoshida

  • Yasuhide Takeuchi

  • Yusuke Shiozawa

  • Yuichi Shiraishi

  • Kenichi Chiba

  • Tetsuichi Yoshizato

  • Hiroko Tanaka

  • Ai Okada

  • Satoshi Nagayama

  • Satoru Miyano

  • Yoshiharu Sakai

  • Seishi Ogawa

Medical Centers

  • Kyoto University, Kyoto, Japan

  • Wellcome Trust Sanger Institute, Cambridge, United Kingdom

  • National Cancer Center Research Institute, Tokyo, Japan

  • The University of Tokyo, Tokyo, Japan

  • Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan

Locations

  • Japan

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Colorectal Cancer

Biomarkers

  • Adenomatous Polyposis Coli

  • AT-rich interactive domain 1A

  • beta-2 microglobulin

  • Phosphatase and tensin homolog

  • Phosphatidylinositol 3-kinase regulatory subunit alpha

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Tumor protein p53

Drug/Treatment

  • TP53

Outcome

  • N/A

Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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