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2643 : ROS dependent PGC1alpha driven mitochondrial biogenesis within the melanoma microenvironment is a pre-requisite for mitochondrial transfer from MSC to malignant cells

Researchers

Presenter

  • Prakrit Kumar

Principal Investigators

  • Jayna Mistry

  • Jamie Moore

  • Charlotte Hellmich

  • Aisha Jibril

  • Christopher Morris

  • Marc Moncrieff

  • Kristian Bowles

  • Stuart Rushworth

Medical Centers

  • The University of East Anglia, Norwich, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Melanoma

Biomarkers

  • Activated leucocyte cell adhesion molecule

  • Cluster of Differentiation 31

  • Cluster of differentiation 45

  • Proto-oncogene tyrosine-protein kinase ROS

  • Melanoma Cell Adhesion Molecule

  • Mesenchymal stem cells

Drug/Treatment

  • Hydrogen peroxide

  • glutathione

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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