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3274 : A robust enhancement of cytokine production in a human chronic activation model of T cell exhaustion in vitro through blockade of PD-1/PDL-1 interactions using pembrolizumab or nivolumab; correlation with dissociated tumor immune cell responses

Researchers

Presenter

  • Omar S. Qureshi

Principal Investigators

  • Lindsay Bentley

  • Tina Tang

  • Fay Stewart

  • Graham Wallace

  • Alison Cooper

  • Aaron Scott

  • David Thickett

  • Babu Naidu

  • Thomas Pinkney

  • Graham Taylor

  • Kristian Brock

  • Louise Healy

  • Zania Stamataki

  • Catherine Brady

  • S J. Curnow

  • John Gordon

  • Nicholas M. Barnes

Medical Centers

  • Celentyx Ltd, Birmingham, United Kingdom.

  • University of Birmingham, Birmingham, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Colorectal Cancer

Biomarkers

  • Peripheral blood mononuclear cell

  • Interferon-gamma

Drug/Treatment

  • Pembrolizumab

  • lonomycin

  • Nivolumab

  • Interferon Gamma

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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