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5220 : Development of first-in-class small molecule inhibitors of FLIP which activate caspase-8, the nodal regulator of apoptosis, necroptosis and pyroptosis

Researchers

Presenter

  • Daniel B. Longley

Principal Investigators

  • Catherine Higgins

  • Jennifer Fox

  • Jamie Z. Roberts

  • Ray Boffey

  • Sophie Williams

  • Trevor Perrior

  • Martin J. Page

  • Tim Harrison

Medical Centers

  • Queen's University Belfast, Belfast, United Kingdom

  • Exonate Ltd, Cambridge, United Kingdom

  • Independent Drug Development Advisor, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Non Small Cell Lung cancer

Biomarkers

  • Epidermal growth factor receptor

  • KRAS proto-oncogene, GTPase

Drug/Treatment

  • selumetinib

  • Tagrisso

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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