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P6-04-18 : The regulatory role of activating transcription factor-2 (ATF2) in modulating tamoxifen resistance in estrogen-receptor positive breast cancer

Researchers

Presenter

  • Athina Giannoudis

Principal Investigators

  • Mohammed I Malki

  • Hisham Mohammed

  • Bharath Rudraraju

  • Suraj Menon

  • Simak Ali

  • Jason S Carroll

  • Carlo Palmieri

Medical Centers

  • University of Liverpool, Institute of Translational Medicine, Liverpool, United Kingdom

  • Oregon Health and Science University, Knight Cancer Institute School of Medicine, Portland, OR

  • Astra Zeneca, Cambridge, United Kingdom

  • Imperial College London, Medicine, London, United Kingdom

  • University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Musculoskeletal

Disease

  • Breast cancer

  • Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis

Biomarkers

  • Glial cell-derived neurotrophic factor

Drug/Treatment

  • Tamoxifen

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A