// App-Quantinova.ai

B : B Oxidized PKARIα protects against ischemia-reperfusion injury by inhibiting lysosomal-triggered calcium release

Researchers

Presenter

  • Jillian N Simon

Principal Investigators

  • Besarte Vrellaku

  • Stefania Monterisi

  • Sandy Chu

  • Nadiia Rawlings

  • Oliver Lomas

  • Gerard A Marchal

  • Dominic Waithe

  • Parag Gajendragadkar

  • Raja Jayaram

  • Rana Sayeed

  • Keith M Channon

  • Pawel Swietach

  • Manuela Zaccolo

  • Philip Eaton

  • Barbara Casadei

Medical Centers

  • Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford

  • Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

  • Wolfson Imaging Centre, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK

  • Cardiothoracic Surgery, Oxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

  • William Harvey Research Institute, Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Ischemia-reperfusion injury

  • Coronary Artery Disease

  • Myocardial injury

  • Ischemic injury

Biomarkers

  • Cyclic AMP-dependent protein kinase

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved