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BSH19‐PO‐096 : Circulating tumour DNA analysis to detect clonal evolution in TP53 mutated CLL treated with sequential precision medicines

Researchers

Presenter

  • C.S. Trethewey

Principal Investigators

  • R.A. Jackson

  • H.S. Walter

  • M.J. Ahearne

  • S.P.N. Jayne

  • M.J.S. Dyer

Medical Centers

  • Leicester Cancer Research Centre,University of Leicester,Leicester,United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • MutS protein homolog 2

  • B-cell lymphoma 2

  • Bruton tyrosine kinase

  • Peripheral blood mononuclear cell

  • Phospholipase C-gamma-2

  • DNA Damage Inducible Transcript 3

  • Immunoglobulin heavy-chain variable region gene

  • Tumor protein p53

  • Circulating DNA

Drug/Treatment

  • Tirabrutinib

  • Venetoclax

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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