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BSH19‐PO‐006 : Identification of signalling pathways regulated by KDM4A in MLL‐AF9 AML via a novel kinase activity screen

Researchers

Presenter

  • S. Patterson

Principal Investigators

  • L. Monaghan

  • Y.-C. Hsieh

  • J. Hay

  • A. Michie

  • X. Huang

Medical Centers

  • Paul O?Gorman Leukaemia Research Centre, University of Glasgow, Glasgow, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute myelocytic leukemia

Biomarkers

  • Mitogen-activated protein kinase 3

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Protein AF-9

  • Cyclin dependent kinase 1

  • Extracellular signal-regulated kinase

  • Focal Adhesion Kinase

  • Histone-lysine N-methyltransferase 2A

  • Janus kinase 3

  • L-serine

Drug/Treatment

  • Interleukin

  • MK8353

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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