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BSH19‐OR‐005 : Targeting metabolic vulnerabilities and aberrant signal transduction pathways in paediatric T‐cell Acute Lymphoblastic Leukaemia (T‐ALL)

Researchers

Presenter

  • L. Anselmi

Principal Investigators

  • B. Accordi

  • V. Serafin

  • M. Zavatti

  • L. Braglia

  • M. Paganin

  • F. Chiarini

  • S. Bresolin

  • S. Patterson

  • M. Ruzzene

  • A.M. Martelli

  • G. Basso

  • X. Huang

  • S. Marmiroli

Medical Centers

  • Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

  • Istituto di Ricerca Pediatrica Città della Speranza (IRP), Padova

  • Department ChiMOMo, University of Modena and Reggio Emilia, Modena

  • Department of Biomedical and Neuromotor Sciences, University of Bologna Italy, Bologna, Italy

  • Institute of Molecular Genetics, Istituto Ortopedico Rizzoli, Bologna, Italy

  • Paul O’ Gorman Leukaemia Research Centre, Glasgow, United Kingdom

  • Dept. of Chemical Sciences, University of Padova, Padova, Italy

Locations

  • Italy

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

  • Oncology (ONC)

Disease

  • T-cell acute lymphoblastic leukemia

  • Tuberculosis

  • Solid malignancies

Biomarkers

  • Neurogenic locus notch homolog protein 1

  • Breakpoint Cluster Region

  • Casein Kinase II

  • Phosphatase and tensin homolog

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Phosphorylated 4E-binding protein 1

  • Serine/threonine-protein kinase mTOR

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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