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BSH2020‐PO‐001 : Whole genome profiling of adult B‐other acute lymphoblastic leukaemia on the UKALL14 trial

Researchers

Presenter

  • D. Leongamornlert

Principal Investigators

  • E. Barretta

  • S. Lee

  • T. Creasey

  • R. Mitchell

  • A. Kirkwood

  • L. Clifton-Hadley

  • P. Patrick

  • P. Campbell

  • B. Patel

  • A. Moorman

  • A. Fielding

  • E. Papaemmanuil

Medical Centers

  • Wellcome Sanger Institiute, Hinxton

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Department of Haematology,UCL Cancer Institute,London,Royaume-uni

  • Cancer Research UK and UCL Cancer Trials Centre, University College London, London, United Kingdom

  • Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institiute, Hinxton

  • Department of Haemato‐Oncology, Barts Cancer Institute, London, UK

  • Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

  • Genetic Disorder

Disease

  • Seizures, scoliosis, and macrocephaly syndrome

Biomarkers

  • Abelson murine leukemia viral oncogene homolog

  • Abelson murine leukemia viral oncogene homolog 2

  • Breakpoint Cluster Region

  • Paired box 5

  • CCAAT enhancer binding protein alpha

  • Platelet Derived Growth Factor Receptor Beta

  • Cluster of Differentiation 206

  • Cyclin Dependent Kinase Inhibitor 2A

  • ETV6-RUNX1

  • Fibroblast growth factor receptor 1

  • Immunoglobulin heavy-chain variable region gene

  • Isocitrate dehydrogenase 2

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • Double Blind/Blinded

  • Cohort

Phase

  • NA

Study Id's

  • NCT01085617

Sponsors

  • N/A

Result

  • N/A