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1345P : Intracranial efficacy of brigatinib (BRG) in patients (Pts) With crizotinib (CRZ)-refractory anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) and baseline CNS metastases

Researchers

Presenter

  • S.-H.I.Ou

Principal Investigators

  • R.Camidge

  • M.-J.Ahn

  • R.M.Huber

  • M.J.Hochmair

  • S.-W.Kim

  • H.L.West

  • K.L.Reckamp

  • J.R.Molina

  • G.Liu

  • A.Delmonte

  • S.Viteri

  • A.Bearz

  • Y.Summers

  • W.Reichmann

  • D.Kerstein

  • S.N.Gettinger

  • D.-W.Kim

Medical Centers

  • Chao Family Comprehensive Cancer Center, University of California, Irvine School of Medicine, Orange, CA

  • Medical Oncology Unit, University Hospital of Parma, Parma, Italy

  • Cancer Center, University of Colorado, Aurora, CO, USA

  • Department of Hematology and Oncology, Samsung Medical Center, Seoul, Republic of Korea

  • Respiratory Medicine and Thoracic Oncology, University of Munich, Munich, Germany.

  • Respiratory Oncology Unit, Otto Wagner Hospital, Vienna, Austria

  • Department of Surgery, Asan Medical Center, Seoul, Korea, Republic of

  • Thoracic Oncology Program, Swedish Cancer Institute, Seattle, WA, USA

  • Clinical Research Operations, City of Hope, Duarte, CA, USA

  • Department of Oncology, Mayo Clinic, Rochester, MN

  • Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON, Canada

  • Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy

  • Medical Oncology, QuirónSalud Dexeus University Hospital, Instituto Oncológico Dr Rosell (IOR), Barcelona, Spain

  • Division of Medical Oncology A, National Cancer Institute, Aviano, Italy

  • Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom

  • Biomedical Data Sciences and Information, ARIAD Pharmaceuticals Inc., Cambridge, MA, USA

  • Clinical Research, ARIAD Pharmaceuticals Inc., Cambridge, MA, USA

  • Yale Cancer Center, Yale School of Medicine, New Haven, CT

  • Departments of Internal Medicine, Seoul National University Hospital, Seoul, Korea

Locations

  • United States

  • Italy

  • Germany

  • Austria

  • Canada

  • Spain

  • United Kingdom

  • Republic of South Korea

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • Anaplastic lymphoma Kinase

Drug/Treatment

  • brigatinib

  • Crizotinib

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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