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392 : Anti-CD40 mAb Promotes Kidney Immunoregulatory Capacity in NHP Transplants by Altering Kidney Tubular Cell (TEC) Expression of CD40 and IL-6.

Researchers

Presenter

  • J. Arp

Principal Investigators

  • Y. Ma

  • H. Yang

  • A. El Warrak

  • A. Haig

  • W. Liu

  • K. Reimann

  • P. Luke

  • Z. Zhang

  • D. Rothstein

  • A. Jevnikar

Medical Centers

  • Medicine, Pathology &amp

  • Microbiology &amp

  • Pathology, Western University, London, ON, Canada

  • Sichuan Cancer Hospital, Chengdu, China

  • University of Massachusetts, Worcester, Worcester, MA

  • University of Pittsburgh, Pittsburgh, PA

Locations

  • Canada

  • China

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • C-C Motif Chemokine Ligand 2

  • Nuclear receptor subfamily 4 group A member 3

  • Peripheral blood mononuclear cell

  • C-C Motif Chemokine Ligand 5

  • Cluster of Differentiation 25

  • Cluster of Differentiation 4

  • RalA Binding Protein 1

  • Interferon-gamma

  • Interleukin 6

  • Interleukin-2

  • Interleukin-8

  • Transforming growth factor beta

  • Regulatory T cells

Drug/Treatment

  • Interferon Gamma

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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