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939 : Stimulator of Interferon Genes (STING)-Induced Endothelial-Mesenchymal Transition (EndMT) Contributes to Interstitial Lung Disease in Sting-Associated Vasculopathy with Onset in Infancy (SAVI) Patients

Researchers

Presenter

  • Louise Malle

Principal Investigators

  • Guibin Chen

  • Bernadette Marrero

  • Gina A. Montealegre Sanchez

  • Yin Liu

  • Gregor Dueckers

  • Suzanne Ramsey

  • Joseph Fontana

  • Rachel VanTries

  • Yan Huang

  • Laisa Santiago

  • Benito Gonzalez

  • Paul Brogan

  • Juergen Brunner

  • Ebun Omoyinmi

  • Athimalaipet V. Ramanan

  • Amy Paller

  • Olcay Y. Jones

  • Seza Ozen

  • Stephen R. Brooks

  • Manfred Boehm

  • Raphaela Goldbach-Mansky

Medical Centers

  • Adriana Almeida de Jesus

  • Translational Autoinflammatory Disease Section (TADS), Laboratory of Clinical Investigation and Microbiology (LCIM), NIAID/NIH, Bethesda, MD

  • Center for Molecular Medicine, NHLBI/NIH, Bethesda, MD

  • Scientific Review Branch, NIAMS, NIH, Bethesda, MD

  • Helios Kliniken - Kinderklinik, HELIOS Klinikum Krefeld, Krefeld, Germany,

  • IWK Health Center, Dalhousie University, Halifax, NS, Canada

  • Cardiovascular and Pulmonary Branch, NIAMS, NHLBI, Bethesda, MD

  • Johns Hopkins All Children's Hospital Rheumatology, Saint Petersburg, FL

  • Luis Calvo Mackenna Hospital, Santiago, Chile

  • Department of Paediatric Rheumatology, UCL Institute of Child Health and Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom

  • Pediatrics, Neonatology, Medical University Innsbruck, Innsbruck, Austria

  • University College London, Institute for Women's Health, London, United Kingdom

  • Bristol Royal Hospital for Children, Bristol, United Kingdom

  • Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL

  • Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD

  • Department of Pediatrics, Division of Neonatology, Erciyes University, Faculty of Medicine, Kayseri, Turkey

  • Biodata Mining and Discovery Section, Office of Science and Technology, NIAMS/NIH, Bethesda, MD

  • Center for Molecular Medicine, NHLBI/NIH, Bethesda, MD

Locations

  • United States

  • Germany

  • Canada

  • Chile

  • United Kingdom

  • Austria

  • Turkey

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

  • Genetic Disorder

Disease

  • N/A

Biomarkers

  • Pore forming protein

  • Interferon

Drug/Treatment

  • Interferon

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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