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2758 : Response to JAK1/2 Inhibition with Baricitinib in “Candle”, “Savi” and “Candle-like” Diseases. a New Therapeutic Approach for Type I IFN-Mediated Autoinflammatory Diseases

Researchers

Presenter

  • Gina A. Montealegre Sanchez

Principal Investigators

  • Suzanne Ramsey

  • Helmut Wittkowski

  • Philip J Hashkes

  • Sara Murias

  • Yackov Berkun

  • Susanne Schalm

  • Jason A Dare

  • Diane Brown

  • Deborah L. Stone

  • Ling Gao

  • Thomas L. Klausmeier

  • John D. Carter

  • Robert Colbert

  • Dawn C. Chapelle

  • Hanna Kim

  • Samantha Dill

  • Adriana Almeida de Jesus

  • Paul Wakim

  • A. Zlotogorski

  • Seza Ozen

  • Paul Brogan

  • Raphaela Goldbach-Mansky

Medical Centers

  • Translational Autoinflammatory Disease Section (TADS), Laboratory of Clinical Investigation and Microbiology (LCIM), NIAID/NIH, Bethesda, MD

  • Faculty of Physicians of the University of Nebraska Medical Center, College of Medicine, Nebraska, NE

  • IWK Health Center, Dalhousie University, Halifax, NS, Canada

  • Pediatric Rheumatology and Immunology, University of Muenster, Munster, Germany

  • Shaare Zedek Medical Center, Jerusalem, Israel

  • Hospital La Paz, Madrid, Spain

  • Hadassah-Hebrew-University-Medical-Cente, Jerusalem, Israel

  • Dr von Hauner Childrens Hospital,, Munich, Germany

  • University of Arkansas for Medical Sciences, Little Rock, AR

  • Cardiology, Childrens Hospital Los Angeles USC, Los Angeles, CA

  • NHLBI/NIH, Bethesda, MD.

  • Riley Hospital for Children, Indianapolis, IN

  • Division of Rheumatology, University of South Florida, Tampa, FL

  • NCATS/NIH, Bethesda, MD

  • Pediatric Translational Research Branch, NIAMS/NIH, Bethesda, MD

  • Biostatistics and Clinical Epidemiology Service, CC, NIH, Bethesda, MD

  • Department of Radiation Oncology, Hadassah Hebrew University Medical Center, Jerusalem, Israel

  • Department of Pediatrics, Division of Neonatology, Erciyes University, Faculty of Medicine, Kayseri, Turkey

  • UCL Institute of Child Health and Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom

Locations

  • United States

  • Canada

  • Germany

  • Israel

  • Spain

  • Turkey

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

  • Genetic Disorder

Disease

  • N/A

Biomarkers

  • N/A

Drug/Treatment

  • Baricitinib

  • Prednisone

  • IFN-lambda

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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