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1833 : iRhom2 Deficiency Protects Fcgr2b-/- Lupus-Prone Mice from Kidney Damage By Modulating ADAM17-Dependent Shedding of TNF-α and EGFR Ligand

Researchers

Presenter

  • Xiaoping Qing

Principal Investigators

  • Yurii Chinenov

  • Patricia M. Redecha

  • Michael Madaio

  • Priya Issuree

  • David McIlwain

  • Tak Mak

  • Carl Blobel

  • Jane E. Salmon

Medical Centers

  • Program in Inflammation and Autoimmunity, Hospital for Special Surgery, New York, NY

  • Arthritis & Tissue Degeneration Program, Hospital for Special Surgery, New York, NY

  • Autoimmunity & Inflammation, Hospital for Special Surgery, New York, NY

  • Medical College of Georgia, Augusta, GA

  • Arthritis & Tissue Degeneration Program, Hospital for Special Surgery, New York, NY

  • Microbiology and Immunology, Stanford University, Stanford, CA

  • Campbell Family Institute for Breast Cancer Research, Princess Margaret Hospital, Toronto, ON, Canada

  • Division of Rheumatology, Hospital for Special Surgery, New York, NY

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • N/A

Biomarkers

  • Epidermal growth factor receptor

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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