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2901 : Anti-Inflammatory Mechanism of Lubricin/Proteoglycan 4 (PRG4) in Monosodium Urate (MSU)-Crystal Induced Arthritis in THP-1 Macrophages Is Mediated By NALP3 Inflammasome.

Researchers

Presenter

  • Anthony M. Reginato

Principal Investigators

  • Changqi Sun

  • Tannin Schmidt

  • Elsaid Khalid

  • Gregory Jay

Medical Centers

  • Division of Rheumatology, The Warren Alpert School of Medicine at Brown University, Providence, RI

  • Division of Rheumatology, The Warren Alpert School of Medicine at Brown University, Providence, RI

  • Schulich School of Engineering, University of Calgary, Calgary, Canada

  • Department of Biomedical and Phramaceutical Science, Chapman University School of Pharmacy, Irvine, CA

  • Emergency Medicine and Engineering, The Warren Alpert Medical School Brown University, Providence, RI

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • N/A

Biomarkers

  • Nuclear factor kappa-light-chain-enhancer of activated B cells

  • Interleukin-8

  • NLR family pyrin domain containing 3

Drug/Treatment

  • Interleukin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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