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: GENE-18. DIVERGENT CLONAL EVOLUTION OF MELANOMA BRAIN METASTASES DURING TREATMENT WITH IMMUNOTHERAPY

Researchers

Presenter

  • Craig Horbinski

Principal Investigators

  • Rasheed Zakaria

  • Farshad Nassiri

  • Gelareh Zadeh

  • David Fisher

  • Maria Martinez-Lage

  • Mario Suva

  • Ryan Sullivan

  • Daniel Cahill

  • Scott Carter

  • Priscilla Brastianos

Medical Centers

  • Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL

  • Liverpool University, Liverpool, United Kingdom

  • MacFeeters-Hamilton Centre for Neuro-Oncology Research, Princess Margaret Cancer Center, Toronto, ON, Canada

  • Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, ON, Canada

  • Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

  • Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

  • Broad Institute of Harvard and MIT, Cambridge, MA

  • Divisions of Neuro-Oncology and Hematology/Oncology, Departments of Medicine and Neurology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA

Locations

  • United States

  • United Kingdom

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • beta-2 microglobulin

  • Programmed death-ligand 1

  • Cluster of differentiation 8A

  • Forkhead Box P3

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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