// App-Quantinova.ai

: Host Matricellular Protein Thrombospondin-1 Limits Extracellular Matrix Proteolysis During Acute Pseudomonas Aeruginosa-Induced Lung Injury

Researchers

Presenter

  • Y. Qu

Principal Investigators

  • T. F. Olonisakin

  • W. Bain

  • M. Hulver

  • Z. Xiong

  • M. E. Zegans

  • R. M. Shanks

  • J. Bomberger

  • J. M. Pilewski

  • A. Ray

  • Z. Cheng

  • P. Ray

  • J. Lee

Medical Centers

  • Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA

  • Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, United States,

  • Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA

  • Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA

  • Department of Surgery/Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Myeloperoxidase

  • Nucleoside diphosphate kinase A

  • Thrombospondin-1

Drug/Treatment

  • thrombospondin-1

  • Elaszym

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A