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504 : Ex Vivo-Expanded Human CD19+CD73–CD25+CD71+TIM-1+ B Regulatory Cells Can Prolong Allograft Survival in a Humanized Mouse Model of Skin Transplantation and Are Dependent on TIM-1-Mediated Regulation of STAT3 Signaling

Researchers

Presenter

  • S. Shankar

Principal Investigators

  • J. Stolp

  • S. Juvet

  • J. Hester

  • K. Wood

Medical Centers

  • Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom

  • The Garvan Institute of Medical Research, Sydney, Australia

  • Toronto General Hospital/Research Institute (UHN), Toronto, ON, Canada

Locations

  • United Kingdom

  • Australia

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • Cluster of Differentiation 19

  • Cluster of Differentiation 25

  • Cluster of Differentiation 4

  • Signal transducer and activator of transcription 3

  • Regulatory T cells

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A