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: LTBK-08. TOCA 511 & TOCA FC VERSUS STANDARD OF CARE IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA

Researchers

Presenter

  • Fabio Iwamoto

Principal Investigators

  • Nina Martinez

  • J Bradley Elder

  • George Kaptain

  • David Cachia

  • Yaron Moshel

  • Steven Brem

  • David Picconi

  • Nam Tran

  • Do-Hyun Nam

  • Chul-Kee Park

  • Joseph Landolfi

  • David Tran

  • Rohan Ramakrishna

  • Karen Fink

  • Deborah Heros

  • Gelareh Zadeh

  • Garth Nicholas

  • Vivek Mehta

  • H Ian Robins

  • Clark Chen

  • Marshall Pitz

  • Jason Heth

  • Seema Nagpal

  • Michael Pearlman

  • Manmeet Ahluwalia

  • Nimish Mohile

  • Ryan Merrell

  • David Schiff

  • Reid Thompson

  • Raphael Davis

  • David Macdonald

  • Thian Kheoh

  • Fairooz Kabbinavar

  • Alexander Lossos

  • Michael Vogelbaum

Medical Centers

  • Pediatric Emergency Medicine, New York-Presbyterian Hospital Columbia University Medical Center, New York, NY

  • NYU Langone Health, New York, NY

  • John Theurer Cancer Center at Hackensack University, Hackensack, NJ, USA

  • UC San Diego Moores Cancer Center, San Diego, CA

  • Lee Moffitt Cancer Center, Tampa, FL, USA

  • Samsung Medical Center, Seoul, Republic of Korea

  • Chonbuk National University Medical School, Jeonju, Korea, Republic of

  • JFK Medical Center, New York, NY, USA

  • Dept of Neurosurgery, University of Florida, Gainesville, FL

  • New York Presbyterian Weill Cornell Medical Center, New York, NY

  • The University of Texas Southwestern Medical Center, Dallas, TX

  • University of Miami, Miami, FL

  • Princess Margaret Cancer Research Institute, University Health Network, Toronto, ON, Canada

  • Ottawa Hospital Cancer Centre, Ottawa, ON, Canada

  • University of Alberta, Edmonton, AB, Canada

  • Cancer Care Manitoba, Winnipeg, MB, Canada

  • Stanford School of Medicine, Stanford, CA

  • Sarah Cannon Research Institute, USA

  • University of Rochester, Rochester, NY

  • NorthShore University HealthSystem, Evanston, IL

  • Stony Brook University, Stony Brook, NY

  • London Regional Cancer Centre, London, ON, Canada

  • Tocagen, San Diego, CA.

  • Hadassah Medical Organization, Jerusalem, Israel

Locations

  • United States

  • Canada

  • Israel

  • Republic of South Korea

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Anaplastic astrocytoma

  • High-Grade Gliomas

  • Glioblastoma

  • Gliomas

Biomarkers

  • Isocitrate dehydrogenase 1

Drug/Treatment

  • Temozolomide

  • Bevacizumab

  • Lomustine

  • vocimagene amiretrorepvec + Toca FC

  • Toca FC (IV)

Outcome

  • N/A


Study Design

  • Randomized

  • Open Label

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A