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: PDTM-22. A C19MC-LIN28A-MYCN ONCOGENIC CIRCUIT DRIVEN BY HIJACKED SUPER-ENHANCERS IS A DISTINCT THERAPEUTIC VULNERABILITY IN ETMRS – A LETHAL BRAIN TUMOR

Researchers

Presenter

  • Iqra Mumal

Principal Investigators

  • Patrick Sin-Chan

  • Tannu Suwal

  • Irtisha Singh

  • Xiao-Nan Li

  • Charles Lin

  • Jeremy Rich

  • Stephen Mack

  • Annie Huang

Medical Centers

  • Hospital for Sick Children, Toronto, ON, Canada

  • Lerner Research Institute, Cleveland, OH.

Locations

  • Canada

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Brain cancer

Biomarkers

  • DNA methyltransferase 3 alpha

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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