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: Inducing Oxidative DNA Damage Overload by Inhibiting the 8oxoguanine Hydrolase MTH1 to Kill Pulmonary Artery Smooth Muscle Cells: A New Therapeutic Strategy in Pulmonary Arterial Hypertension

Researchers

Presenter

  • G. Vitry

Principal Investigators

  • R. Paradis

  • V. Nadeau

  • E. Tremblay

  • S. Provencher

  • O. Boucherat

  • S. Bonnet

  • R. Paulin

Medical Centers

  • Pneumology research, IUCPQ research centre, Québec, QC, Canada.

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Pulmonary arterial hypertension

Biomarkers

  • 8-hydroxy-2' -deoxyguanosine

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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