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: Common and Rare Genetic Determinants of von Willebrand Factor Clearance and Factor VIII‐binding Modify Factor VIII Pharmacokinetics in a Pediatric Hemophilia A Population

Researchers

Presenter

  • L.L. Swystun

Principal Investigators

  • K. Ogiwara

  • O. Rawley

  • C. Brown

  • I. Georgescu

  • W. Hopman

  • V. Labarque

  • C. Male

  • K. Thom

  • V.S. Blanchette

  • M. Carcao

  • D. Lillicrap

Medical Centers

  • Queen's University, Department of Pathology and Molecular Medicine, Kingston, ON, Canada

  • Queen's University, Public Health Sciences, Kingston, ON, Canada

  • University Hospitals Leuven, Department of Paediatric Respiratory Medicine, Leuven, Belgium

  • Medical University of Vienna, Department for Pathology, Vienna, Austria

  • University of Toronto and Division of Hematology/Oncology, Hospital for Sick Children,, Department of Pediatrics, Toronto, Canada

Locations

  • Canada

  • Belgium

  • Austria

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Hemophilia

Biomarkers

  • von Willebrand factor

Drug/Treatment

  • rFVIII

  • FVIII

Outcome

  • N/A

Study Design

  • Pharmacokinetics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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