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: The Intestinal Microbiome Affects Thrombin Generation in Human Subjects Through Effects on Coagulation Related Plasma Protein Levels

Researchers

Presenter

  • Y. Mohammed

Principal Investigators

  • R.S. Kootte

  • W.F. Kopatz

  • C. Borchers

  • H.R. Bller

  • H.H. Versteeg

  • M. Nieuwdorp

  • T.E. Van Mens

Medical Centers

  • Leiden University Medical Center, Center for Proteomics and Metabolomics, Leiden, the Netherlands

  • Univ of Victoria-Genome British Columbia Proteomics Ctr, Victoria, BC, Canada

  • Amsterdam Cardiovascular Sciences, Amsterdam UMC, location AMC, Dept. of Vascular Medicine, Amsterdam, the Netherlands

  • LUMC, Department of Internal Medicine, Einthoven Laboratory for Experimental Vascular Medicine, Leiden, the Netherlands

  • Amsterdam UMC, AMC and VUmc, Departments of Internal Medicine, Amsterdam Diabetes Center, Amsterdam, the Netherlands

Locations

  • Netherlands

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Gastroenterology (GU)

  • Endocrine/metabolic Diseases (ME)

Disease

  • Metabolic syndrome

Biomarkers

  • Nucleoside diphosphate kinase A

Drug/Treatment

  • Evithrom

Outcome

  • N/A


Study Design

  • Randomized

  • Double Blind/Blinded

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A