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WP201 : Angiopoietin-1 Mimetic Peptide Treatment of Stroke Regulates MicroRNA Expression and Promotes Neuroprotection in Type One Diabetic Rats

Researchers

Presenter

  • Michael Chopp

Principal Investigators

  • Ruizhuo Ning

  • Tao Yan

  • Paul Van Slyke

  • Daniel Dumont

Medical Centers

  • Henry Ford Hosp, Detroit, MI

  • Henry Ford Hosp, Northville, MI

  • Sunnybrook Health Sciences Centre, Toronto, ON, Canada

  • Sunnybrook Research Institute, Toronto, ON, Canada

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

  • Genetic Disorder

Disease

  • Diabetes

  • Stroke

  • Type 1 diabetes mellitus

Biomarkers

  • microRNA-155

  • Advanced Glycosylation End-Product Specific Receptor

  • Monocyte chemoattractant protein 1

  • C-C Motif Chemokine Ligand 2

  • MicroRNA 126

  • Translocator protein

  • Tumor necrosis factor

Drug/Treatment

  • Streptozotocin

  • miR155

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim