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19146 : Disruption of TRAF2-TAK1-IKKB Signaling Triggers Mitochondrial Perturbations and Necrotic Cell Death in Doxorubicin Cardiotoxicity

Researchers

Presenter

  • Rimpy Dhingra

Principal Investigators

  • Victoria Margulets

Medical Centers

  • Univ of Manitoba, Winnipeg, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Cardiotoxicity

  • Congestive heart failure

Biomarkers

  • Nucleoside diphosphate kinase A

  • Proto-oncogene tyrosine-protein kinase ROS

  • RalA Binding Protein 1

  • Lactate dehydrogenase

Drug/Treatment

  • Doxorubicin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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